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Facile and convenient new synthesis of imidazobenzimidazol-2-one and pyrimidobenzimidazol-2,3-dione derivatives

Abdelkebir Zarguil, Mohammed Saadouni, Said Boukhris, Nouzha Habbadi, Amina Hassikou, Abdelaziz Souizi

Abstract


 Reaction of epoxides 1 and 2 with 2-aminobenzimidazole led to formation of imidazobenzimidazol-2-ones 4 and pyrimido[1,2-a]benzimidazol-2,3-diones 5, respectively in good yields. This same compound 5 may be obtained by another route by reacting halohydrin derivates 3 with 2-aminobenzimidazole. The mechanisms of the studied reactions are discussed.


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DOI: http://dx.doi.org/10.13171/mjc.1.1.2011.10.06.18

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