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Resorcin[4]arene Sulfonic Acid as New and Efficient Organocatalysts for the One Pot Synthesis of Fused Pyrimidine Derivatives

mahesh shivajirao pandharpatte, Dattatray Pawar, Khudbudin Mulani, Kamini Donde, Nazeruddin Nasiruddin Gulam Mohammed


Abstract: One pot and efficient protocol for the synthesis of fused pyrimidine scaffolds has been established using recyclable resorcin[4]arene tetrasulfonic acid as an energetic organo-catalyst under solvent free condition. Resorcin[4]arene tetrasulfonic acid as a  recyclable organo-catalyst give  excellent yields under solvent free condition  for synthesis of fused pyrimidine derivatives. Non-Toxicity, non-chromatographic purification techniques, high yield and recyclable catalyst make the procedure valuable and environmentally friendly.

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