Singgang as a potential antioxidant and anticancer dish: a review
Abstract
Singgang is one of the popular dishes in Terengganu, Malaysia, that includes fish such as either chub mackerel or Indian mackerel and selected herbs and spices like turmeric, galangal, garlic, sour plum, and chilies. In Asia, these chosen spices and herbs are traditionally defined as any part of a plant that is used in a diet for its aromatic and flavor-enhancing properties. These herbs and spices have highlighted various health benefits to consumers, such as antioxidant, antibacterial, anti-inflammatory, antiproliferative, anticancer, and hypolipidemic. Besides the potential of the singgang dish as a nutritional dish, it was believed that the mixture of fish and selected herbs and spices could synergistically have a positive effect during the cooking process. Herbs and spices have been identified as sources of various phytochemicals, many of which have potential antioxidant activity and have a role in antioxidant defense and redox signaling. In addition, herbs and spices have been identified as anticancers because of their ability to influence the activity of some biomarkers and therefore influence carcinogenic bioactivation. In this review, the roles of selected spices and herbs as antioxidants and anticancer will be discussed, supporting the prospective of the singgang dish as a promising therapeutic mark for future study.
Full Text:
PDFReferences
- A. A. Majid, Ikan singgang berkhasiat sebagai makanan berfungsi untuk penjagaan kesihatan, 2019. https://www.academia.edu/6050784/ikan_singgang_berkhasiat_sebagai_makanan_berfungsi_untuk_penjagaan_kesihatan (accessed 23 March 2019).
- A. Husain, A. Mohammed, Role of curcumin in disease prevention and treatment, Advanced Biomedical Research, 2018, 7, 38.
- A. Chouni, S. Paul, A review on phytochemical and pharmacological potential of Alpinia galanga, Pharmacognosy Journal, 2018, 10, 9-15.
- S. Adaki, R. Adaki, K. Shah, A. Karagir, Garlic: review of literature, Indian Journal Cancer, 2014, 51, 577-581.
- M. Taher, H. Hamidon, D. Susanti, D. Garcinia atroviridis – A review on phytochemicals and pharmacological properties, Marmara Pharmaceutical Journal, 2016, 21, 38-47.
- M. Salem, S. Rohani, E. R. Gillies, Curcumin, a promising anticancer therapeutic: a review of its chemical properties, bioactivity and approaches to cancer cell delivery, RSC Advances, 2014, 10815–10829.
- P. Mishra, B. Paital, S. Jena, S. S. Swain,S. Kuma, M. K. Yadav, G. B. N. Chainy, L. Samanta, Possible activation of NRF2 by Vitamin E / Curcumin against altered thyroid hormone-induced oxidative stress via NFĸB / AKT / mTOR / KEAP1 signaling in rat heart, Science Reports, 2019, 9, 1–16.
- R. Joshi, R. Gangabhagirathi, Antioxidant activity of capsaicin on radiation-induced oxidation of murine hepatic mitochondrial membrane preparation, Research and Reports in Biochemistry, 2015, 163-171.
- K. A. Szychowski, U. E. Binduga, K. Rybczyńska-Tkaczyk, L. M. Leja, J. Gmiński, Cytotoxic effects of two extracts from garlic (Allium sativum L.) cultivars on the human squamous carcinoma cell line SCC-15, Saudi Journal of Biological Sciences, 2018, 25, 1703–1712.
- H. Huang, A. Y. Chen, X. Ye, R. Guan, G. O. Rankin, Y. C. Chen, Galangin, a flavonoid from lesser galangal, induced Apoptosis via p53-dependent pathway in ovarian cancer cells, Molecules, 2020, 25, 1–19.
- G. Secci, G. Parisi, From farm to fork : lipid oxidation in fish products, a review, Italian Journal of Animal Science, 2016, 1, 124-136.
- T. Freshwater, F. Clarias, C. Carpio, Tc. Hm, W. Tchoumbougnang, F. C. Ndomou, S. Nganou, K. Pankaj, B. Teboukeu, Effect of smoking on the oxidation parameters and the total phenolic effect of smoking on the oxidation parameters and the total phenolic compounds of two freshwater fishes : Clarias Gariepinus and Cyprinus Carpio, Journal of Food Processing and Technology, 2018, 9, 754.
- H. Y. Mastura, H. Hasnah, Y. T. Yap, Total phenolic content and antioxidant capacities of instant mix spices cooking pastes, International Food Research Journal, 2017, 24, 68–74.
- S. Inchuen, P. Pornchaloempong, Influence of heat treatment on antioxidant capacity and color of thai red curry paste, Kasetsart Journal – Natural Science, 2011, 45, 136–146.
- F. N. Ahlina, N. Nugraheni, I. A. Salsabila, S. Haryanti, M. Da'i, E. Meiyanto, Revealing the reversal effect of galangal (Alpinia galanga L.) extract against oxidative stress in metastatic breast cancer cells and normal fibroblast cells intended as a Co- chemotherapeutic and anti-ageing agent, Asian Pacific Journal of Cancer Prevention, 2020, 21, 107–117.
- J. Y. Wang, X. Wang, X. J. Wang, B. Z. Zheng, Y. Wang, X. Wang, B. Liang, Curcumin inhibits the growth via Wnt/γ-catenin pathway in non-small-cell lung cancer cells, European Review for Medical and Pharmacological Sciences, 2018, 22, 7492–7499.
- Y. Wang, X. Deng, C. Yu, G. Zhao, J. Zhou, G. Zhang, M. Li, D. Jiang, Z. Quan, Y. Zhang, Synergistic inhibitory effects of capsaicin combined with cisplatin on human osteosarcoma in culture and in xenografts, Journal of Experimental & Clinical Cancer Research, 2018, 37, 1–17.
- B. Halliwell, J. M. C. Gutteridge, Free Radicals in Biology and Medicine, 5th ed, Oxford University Press: Oxford, UK, 2015.
- R. Apak, M. Özyürek, K. Güçlü, E. Çapanoʇlu, Antioxidant activity/capacity measurement. 1. Classification, physicochemical principles, mechanisms, and electron transfer (ET)-based assays, Journal of Agricultural and Food Chemistry, 2016, 64, 997–1027.
- I. Pinchuk, H. Shoval, Y. Dotan, D. Lichtenberg, Evaluation of antioxidants: Scope, limitations, and relevance of assays, Chemistry and Physics of Lipids, 2012, 165, 638–647.
- D. M. Kasote, S. S. Katyare, M. V. Hegde, H. Bae, Significance of antioxidant potential of plants and its relevance to therapeutic applications, International Journal of Biological Sciences, 2015, 11, 982–991.
- D. Krishnaiah, R. Sarbatly, R. A. Nithyanandam, review of the antioxidant potential of medicinal plant species, Food and Bioproducts Processing, 2011, 89, 217–233.
- D. M. Kasote, V. M. Hegde, S. S. Katyare, Mitochondrial dysfunction in psychiatric and neurological diseases: Cause(s), consequence(s), and implications of antioxidant therapy, BioFactors, 2013, 39, 392–406.
- N. A. Anwar, A. N. Jamain, N. Ridzwan, M. N. Jumli, N. A. Hadi, M. Adzim, K. Rohin, R. Arshad, C. Abdullah, A. Bakar, A. Z. Latif, Study on total phenolic, flavonoid and antioxidant capacity of fish singgang extracts, Journal of Pharmaceutical Research International, 2021, 33, 12–21.
- A. Tomaino, F. Cimino, V. Zimbalatti, V. Venuti, V. Sulfaro, A. De Pasquale, A. Saija, Influence of heating on antioxidant activity and the chemical composition of some spice essential oils, Food Chemistry, 2005, 89, 549–554.
- X. Gao, Z. Xue, Q. Ma, Q. Guo, L. Xing, R. K. Santhanam, M. Zhang, H. Chen, Antioxidant and anti-hypertensive effects of garlic protein and its hydrolysates and the related mechanism, Journal of Food Biochemistry, 2020, 44, 1–12.
- M. Chatatikun, P. Supjaroen, P. Promlat, C. Chantarangkul, S. Waranuntakul, J. Nawarat, J. Tangpong, A. Chiabchalard, Antioxidant and tyrosinase inhibitory properties of an aqueous extract of Garcinia atroviridis Griff. ex. T. Anderson fruit pericarps, Pharmacognosy Journal, 2020, 12, 71–78.
- L. Panzella, A. Napolitano, Natural and bioinspired phenolic compounds as tyrosinase inhibitors for the treatment of skin hyperpigmentation: recent advances, Cosmetics, 2019, 6, 57.
- S. Zolghadri, A. Bahrami, M. T. Hassan Khan, J. Munoz-Munoz, F. Garcia-Molina, F. Garcia-Canovas, A. A. Saboury, A comprehensive review on tyrosinase inhibitors, Journal of Enzyme Inhibition and Medicinal Chemistry, 2019, 34, 279–309.
- B. Bozin, N. Mimica-dukic, I. Samojlik, A. Goran, R. Igic, Phenolics as antioxidants in garlic (Allium sativum L . Alliaceae), Food Chemistry, 2008, 111, 925–929.
- K. M. Nelson, J. L. Dahlin, J. Bisson, J. Graham, G. F. Pauli, M. A. Walters, The essential medicinal chemistry of curcumin, Journal of Medicinal Chemistry, 2017, 60, 1620–1637.
- M. Ivanovi, Comparative study of chemical composition and antioxidant activity of essential oils and crude extracts of four characteristic Zingiberaceae herbs, Plants-Basel, 2021, 10, 501.
- J. C. H. Singh, V. Alagarsamy, S. S. Kumar, Y. N. Reddy, Neurotransmitter metabolic enzymes and antioxidant status on alzheimer's disease induced mice treated with Alpinia galanga ( L .) wild, Phytotherapy Research, 2011, 25, 1061–1067.
- W. N. Tan, K. C. Wong, M. Khairuddean, I. M. Eldeen, Z. M. Asmawi, B. Sulaiman, Volatile constituents of the fruit of Garcinia atroviridis and their antibacterial and anti-inflammatory activities, Flavour and Fragrance Journal, 2013, 28, 2–9.
- M. Hamed, D. Kalita, M. E. Bartolo, S. S. Jayanty, Capsaicinoids, polyphenols and antioxidant activities of Capsicum annuum : comparative study of the effect of ripening stage and cooking methods, Antioxidants, 2019, 8, 364.
- A. R. Alvarez, Stable complexes involving acetylcholinesterase and amyloid-beta peptide change the biochemical properties of the enzyme and increase the neurotoxicity of alzheimer's fibrils, Journal of Neuroscience, 1998, 18, 3213–3223.
- C. W. Abell, S. W. Kwan, Molecular characterization of monoamine oxidases A and B, Progress in Nucleic Acid Research and Molecular Biology, 2001, 65, 129-156.
- E. Carmeli, A. Bachar, S. Barchad, M. Morad, J. Merrick, Antioxidant status in the serum of persons with intellectual disability and hypothyroidism: A pilot study, Research in Developmental Disabilities, 2008, 29, 431–438.
- R. Mogulkoc, A. K. Baltaci, L. Aydin, E. Oztekin, A. Sivrikaya, The effect of thyroxine administration on lipid peroxidation in different tissues of rats with hypothyroidism, Acta Physiologica Hungarica, 2005, 92, 39–46.
- D. A. Dickinson, K. E. Iles, H. Zhang, V. Blank, H. J. Forman, Curcumin alters EpRE and AP-1 binding complexes and elevates glutamate-cysteine ligase gene expression, The FASEB Journal, 2003, 17, 1–26.
- A. Dairam, R. Fogel, S. Daya, J. L. Limson, Antioxidant and iron-binding properties of curcumin, capsaicin, and S-allylcysteine reduce oxidative stress in rat brain homogenate, Journal of Agricultural and Food Chemistry, 2008, 56, 3350–3356.
- A. Galano, A. Martínez, Capsaicin, a tasty free radical scavenger: mechanism of action and kinetics, Journal of Physical Chemistry B, 2012, 116, 1200–1208.
- S. Luqman, S. I. Rizvi, Protection of lipid peroxidation and carbonyl formation in proteins by capsaicin in human erythrocytes subjected to oxidative stress, Phytotherapy Research, 2006, 20, 303–306.
- A. N. Jamain, N. A. Anwar, N. Ridzwan, M. N. Jumli, N. A. Hadi, R. Arshad, M. Adzim, K. Rohin, C. Abdullah, A. Bakar, A. Z. A. Latif, Fish singgang extracts as a potential anti-proliferative against colon cancer cell lines, Journal of Pharmaceutical Research International, 2021, 33, 126–136.
- M. N. Hall, J. E. Chavarro, I. M. Lee, W. C. Willett, J. Ma, A 22-year prospective study of fish, n-3 fatty acid intake, and colorectal cancer risk in men, Cancer Epidemiology Biomarkers and Prevention, 2008, 17, 1136–1143.
- S. Huerta-Yépez, A. B. Tirado-Rodriguez, O. Hankinson, Role of diets rich in omega-3 and omega-6 in the development of cancer, Boletin Medico del Hospital Infantil de Mexico, 2016, 73, 446–456.
- S. Norouzi, M. Majeed, M. Pirro, D. Generali, A. Sahebkar, curcumin as an adjunct therapy and microRNA modulator in breast cancer, Current Pharmaceutical Design, 2018, 24, 171–177.
- E. Kronski, M. E. Fiori, O. Barbieri, S. Astigiano, V. Mirisola, P. H. Killian, A. Bruno, A. Pagani, F. Rovera, U. Pfeffer, C. P. Sommerhoff, D. M. Noonan, A. G. Nerlich, L. Fontana, B. E. Bachmeier, MiR181b is induced by the chemopreventive polyphenol curcumin and inhibits breast cancer metastasis via down-regulation of the inflammatory cytokines CXCL1 and -2, Molecular Oncology, 2014, 8, 581–595.
- J. Guo, W. Li, H. Shi, X. Xie, L. Li, H. Tang, M. Wu, Y. Kong, L. Yang, J. Gao, P. Liu, W. Wei, X. Xie, Synergistic effects of curcumin with emodin against the proliferation and invasion of breast cancer cells through upregulation of miR-34a, Molecular and Cellular Biochemistry, 2013, 382, 103–111.
- J. Yang, Y. Cao, J. Sun, Y. Zhang, Curcumin reduces the expression of Bcl-2 by upregulating miR-15a and miR-16 in MCF-7 cells, Medical Oncology, 2010, 27, 1114–1118.
- H. Hermeking, The miR-34 family in cancer and Apoptosis, Cell Death and Differentiation, 2010, 17, 193–199.
- W. T. Kim, S. P. Seo, Y. J. Byun, H. W. Kang, Y. J. Kim, S. C. Lee, P. Jeong, Y. Seo, S. Y. Choe, D. J. Kim, S. K. Kim, S. K. Moon, Y. H. Choi, G. T. Lee, I. Y. Kim, S. J. Yun, W. J. Kim, Garlic extract in bladder cancer prevention: Evidence from T24 bladder cancer cell xenograft model, tissue microarray, and gene network analysis, International Journal of Oncology, 2017, 51, 204–212.
- M. Hayashi, S. Nomoto, M. Kanda, Y. Okamura, Y. Nishikawa, S. Yamada, T. Fujii, H. Sugimoto, S. Takeda, Y. Kodera, Identification of the kinase anchor protein 12 (AKAP12) gene as a candidate tumor suppressor of hepatocellular carcinoma, Journal of Surgical Oncology, 2012, 105, 381–386.
- D. K. Yoon, C. H. Jeong, O. H. Jun, H. K. Chun, J. H. Cha, J. H. Seo, Y. H. Lee, K. Y. Choi, B. J. Ahn, S. K. Lee, W. K. Kim, AKAP12 induces apoptotic cell death in human fibrosarcoma cells by regulating CDKI-cyclin D1 and caspase-3 activity, Cancer Letters, 2007, 254, 111–118.
- M. S. Ioannou, E. S. Bell, M. Girard, M. Chaineau, J. N. R. Hamlin, M. Daubaras, A. Monast, M. Park, L. Hodgson, P. S. McPherson, DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior, Journal of Cell Biology, 2015, 208, 5, 629–648.
- Y. S. Lee, Y. S. Kang, J. S. Lee, S. Nicolova, J. A. Kim, Involvement of NADPH oxidase-mediated generation of reactive oxygen species in the apototic cell death by capsaicin in HepG2 human hepatoma cells, Free Radical Research, 2004, 38, 405–412.
- K. C. Pramanik, S. R. Boreddy, S. K. Srivastava, Role of mitochondrial Electron transport chain complexes in capsaicin mediated oxidative stress leading to Apoptosis in pancreatic cancer cells, PLoS ONE, 2011, 6, e20151.
- A. M. Sánchez, S. Malagarie-Cazenave, N. Olea, D. Vara, A. Chiloeches, I. Díaz-Laviada, Apoptosis induced by capsaicin in prostate PC-3 cells involves ceramide accumulation, neutral sphingomyelinase, and JNK activation, Apoptosis, 2007, 12, 2013–2024.
- M. H. Lin, Y. H. Lee, L. H. Cheng, H. Y. Chen, H. F. Jhuang, P. J. Chueh, Capsaicin inhibits multiple bladder cancer cell phenotypes by inhibiting tumor-associated NADH oxidase (tNOX) and sirtuin1 (SIRT1), Molecules, 2016, 21, 1–14.
- T. Shimura, N. Noma, T. Oikawa, Y. Ochiai, S. Kakuda, Y. Kuwahara, Y. Takai, A. Takahashi, M. Fukumoto, Activation of the AKT/cyclin D1/Cdk4 survival signaling pathway in radioresistant cancer stem cells, Oncogenesis, 2012, 1, e12.
- M. A. Parasramka, S. Ali, S. Banerjee, T. Deryavoush, F. H. Sarkar, S. Gupta, Garcinol sensitizes human pancreatic adenocarcinoma cells
to gemcitabine in association with microRNA signatures, Molecular Nutrition and Food Research, 2013, 57 (2), 235–248.
- M. L. Tsai, Y. S. Chiou, Y. L. Chiou, C. T. Ho, M. H. Pan, Garcinol suppresses inflammation-associated colon carcinogenesis in mice, Molecular Nutrition and Food Research, 2014, 58,1820–1829.
DOI: http://dx.doi.org/10.13171/mjc02401261761khalil_rohin
Refbacks
- There are currently no refbacks.
Copyright (c) 2024 Mediterranean Journal of Chemistry